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Our favorite Week 12 college football bets

By VSiN Staff  ( 

November 20, 2021 09:10 AM

It is Week 12 and our guys are on a hot streak, posting a 25-10-1 record over the last three weeks. We've got another round of games on the docket and another set of picks for your consideration.

Our handicappers Adam Burke, Tim Murray, Scott Seidenberg and Wes Reynolds are here to give you their best bets for the weekend's card.

Overall record: 59-50-4 ATS

Lines are consensus odds from VSiN's college football lines page, as of Wednesday night.

Saturday, Nov. 20

Iowa State Cyclones at No. 12 Oklahoma Sooners (-4, 59.5)

Noon ET

Seidenberg: If Oklahoma loses this game, I don’t want to hear from Lincoln Riley until next season. Last week’s debacle at Baylor was just that, a debacle. Now, how do you pick yourself up and stay the course? 

Oklahoma’s season is not over. Despite people writing them off for the CFB playoff, that’s actually not the case. Oklahoma will have a decent shot to get in if they win the next 3 games, finish as 12-1 Big 12 champs and watch a team like Oregon lose to Utah either this week or in the Pac 12 title game. That has to be the message from Riley to his team. Let everyone count them out, let everyone forget about them, and go out and win the Big 12 in convincing fashion and give the committee something to think about. 

Iowa State comes into this game off a gut-wrenching loss to Texas Tech last week. This team has not had the season that was expected. Matt Campbell took a lot of heat after a press conference this week when he said his goal was not winning the Big 12. I'm sure that had to rub some of his players the wrong way. Plus, his name is being floated around a lot of coaching rumors. That distraction, plus a disheartened team, could be enough for the Cyclones to lay an egg here in Norman. I expect the Sooners to bounce back in a big way and roll, keeping their Big 12 title goals alive and well. 

Pick: Oklahoma -4


Rutgers Scarlet Knights at Penn State Nittany Lions (-17.5, 47)

Noon ET

Burke: With last week’s blowout win over Indiana, the bowl dream is alive and well for Rutgers. The Scarlet Knights need to win one of the next two games against either Penn State or Maryland to give themselves a chance at the program’s first bowl appearance since 2014.

Penn State already has six wins, but the season has been a disappointment. The win over Auburn feels like an eternity ago and the Nittany Lions squandered a 4-0 start with losses to Iowa, Illinois, Ohio State and now Michigan. One more crack at a win over a ranked team comes next week in East Lansing against Michigan State.

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